Heterogeneous Catalysis

Features

Important Features:

• Bench top to plant scale
  Our devices are well-characterized and directly scalable from lab to pilot to production.
• Modularity & Configuration Customization
  The reactor components (“blocks”) are modular layers which can be arranged in a custom order to build the perfect reactor configuration (“tower”) for any type of chemistry.
• Minimal internal volume
  Our devices drastically reduce dead volume making the process safer while minimizing footprint and reagents consumption.
• Continuous operation
  Our devices can boost productivity and can be easily used and integrated within either a batch process or a continuous one.

Other Advantages:

• Cost effective
  Our devices come at a lower price than competing technologies. Our devices also
  reduce your operating costs thanks to minimal maintenance and highly efficient
  performance.
• Excellent chemical compatibility
  Machined in materials with excellent chemical resistance, Zaiput separators work
  with a wide range of organic solvents, in acidic and basic solutions.
• Green technology
  Our devices have excellent reaction performance and high yield and selectivity, boosting productivity.
  They are suitable for any catalytic reaction process, from bulk to high-value chemical industries.
• Pressure rating
  The metal design allows Zaiput reactors to be used in-line with a pressurized
  process (up to 35 Bar).
• Inherently safe
  No electricity is required, no headspace, and minimal internal volume.
• Easy usage and maintenance
  Plug and play functionality at all scales.
• Rapid Scaling
  Processes can be optimized at the lab scale and then directly scaled to production
  quickly thanks to the scaling geometry factor which maintains residence time and
  performance constant across scales.

How It Works

Zaiput Flow Technologies’ patented reactors allow to carry out continuous heterogenous
catalysis reactions (usually gas-liquid-solid catalyst) by optimizing the flow distribution
of the reagents through the device while maximizing catalyst utilization.

• The two inlet streams (usually one liquid and one gas) enter the reactor at the bottom where they are mixed and distributed uniformly in the effective cross-section of the reactor.
• By stacking different modules, such as mixing cartridges, catalytic cartridges, and heat exchanger modules, the reagents travel upward to a customized reactor configuration which can be optimized for a specific chemistry.
• Reaction will happen in the catalytic layers, while mixing and heat exchange modules guarantee tight and efficient control over the reaction process.
• The internal structure of the reactor components enhances mixing and mass transfer while maintaining plug flow characteristics. By flowing the reagents through the catalytic layer (rather than by) improves performance by lowering the characteristic length for mass transfer.
• The reactor is also designed to maintain a constant temperature inside even when conditions are fluctuating.
• The fluids then exit the reactor on the top from the outlet piece.

Catalyst Options

Packing your own catalyst

Zaiput also offers the possibility to use your own catalyst of choice inside our reactor. To do this, Zaiput has developed a “pack your own cartridge” concept where these packed cartridges can also be placed and used inside the reactor. Zaiput offers a packing setup that allows you to have a user-friendly, repeatable, and systematic way to pack those cartridges.

Contact us if you are interested in this option or would like to hear more about it. If you have any questions, contact us at support@zaiput.com

Applications

Zaiput reactor can be used to carry out many different classes of reactions such as:

• Deprotection
• Nitro reduction
• Double bond reduction
• Carbonyl reduction
• Deoxygenation
• Dehalogenation
• Oxygenation
• And more

Zaiput reactor allows to carry out these reactions in a small confined space with minimal head volume strongly improving on safety compared to batch approaches. Performance is also improved thanks to the substantial engineering design behind the reactor structure and its components.

Literature

Scientific articles featuring our separators:

Breen, Sean & Barua, Purnima & Fang, Yuan-Qing & Ford, David & Hasan, Ali & Joshi, Manish & Mason, Sara & Nagy, Kevin & Quadery, Sifat & Russell, Grace & Nikolakis, Vladimiros & Holcombe, John & Adamo, Andrea & Milani, Lorenzo. (2025). A Continuous Hydrogenation Reactor Based on a Powdered Catalyst Enmeshed in an Expanded Poly(tetrafluoroethylene) Matrix. Organic Process Research & Development. 10.1021/acs.oprd.4c00303.

Specifications

Tower Reactor – Laboratory Scale

	Part Number	TWR-10
	Maximum Pressure	35 Bar (500 psi)
	Wetted Parts	316-SS or Hastelloy C276, PTFE, FFKM
	Liquid Flow Rate	~ 0.5-10 mL/min
	Max Temperature	200°C
	Gas Flow Rate	~ 20-500 sccm

*Scroll left to see more of the table

Tower Reactor – Pilot Scale

	Part Number	TWR-100
	Maximum Pressure	35 Bar (500 psi)
	Wetted Parts	316-SS or Hastelloy C276, PTFE, FFKM
	Liquid Flow Rate	~ 10-100 mL/min
	Max Temperature	200°C
	Gas Flow Rate	~ 300-5000 sccm

*Scroll left to see more of the table

Tower Reactor – Small Production Scale

	Part Number	TWR-1000
	Maximum Pressure	35 Bar (500 psi)
	Wetted Parts	316-SS or Hastelloy C276, PTFE, FFKM
	Liquid Flow Rate	~ 100-1000 mL/min
	Max Temperature	200°C
	Gas Flow Rate	~ 3-50 slm

*Scroll left to see more of the table

Tower Reactor – Large Production Scale

	Part Number	TWR-10K
	Maximum Pressure	35 Bar (500 psi)
	Wetted Parts	316-SS or Hastelloy C276, PTFE, FFKM
	Liquid Flow Rate	~ 1-10 L/min
	Max Temperature	200°C
	Gas Flow Rate	~ 30-500 slm

*Scroll left to see more of the table

Ordering Information

FAQ

FAQs about Zaiput reactors